Chapter 9
Magnetic Nanoparticles for Drug Delivery

9.1 Introduction 9.2 Experimental Design 9.3 Materials 9.3.1 Reagents 9.3.2 Facilities/Equipment 9.4 Methods 9.4.1 Synthesis of Magnetic Nanoparticles 9.4.2 Physical Characterization of Magnetic Nanoparticles 9.4.3 Conversion of Dox·Hcl 9.4.3.1 Convert Dox·Hcl into Water-Insoluble Doxorubicin 9.4.3.2 Doxorubicin in Solution 9.4.4 Drug Loading and Release Kinetics 9.4.4.1 Drug Loading 9.4.4.2 Determine Drug Loading 9.4.5 Kinetics of Dox Release from Magnetic Nanoparticles 9.4.6 Anti-Proliferative Activity of Doxorubicin Loaded Magnetic Nanoparticles on Mcf-7 Cells 9.4.7 Anti-Proliferative Activity of Doxorubicin Loaded Magnetic Nanoparticles on Mcf-7 Cells In The Presence Of A Magnetic Field 9.5 Data Acquisition, Anticipated Results, and Interpretation 9.6 Discussion and Commentary 9.7 Troubleshooting Table 9.8 Application Notes 9.9 Summary Points   Acknowledgement   Annotated References

Chapter 10
Imaging and Therapy of Atherosclerotic Lesions with Theranostic Nanoparticles

10.1		Introduction
10.2		Experimental Design
10.3		Materials
10.3.1		Reagents
10.3.2		Facilities/Equipment
10.3.3		Animal Model
10.3.4		Alternate Reagents And Equipment
10.4		Methods
10.4.1		Synthesis of Theranostic Nanoparticles
10.4.2		Intravital Fluorescence Microscopy
10.4.3		Light-Based Therapy
10.5		Data Acquisition, Anticipated Results, And Interpretation
10.5.1		Characterization of Theranostic Nanoparticles
10.5.2		Animal Experimentation
10.5.3		Intravital Fluorescence Microscopy
10.5.4		Statistical Analyses
10.5.5		Anticipated Results
10.6		Discussion and Commentary
10.7		Troubleshooting Table
10.8		Summary Points
10.9		Acknowledgements
10.10		References

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