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Chapter 9
Application of the Benchmark Approach in the Correlation of In Vitro and
In Vivo Data in Developmental Toxicity
| 9.1 |
 |
Introduction |
| 9.2 |
Materials and Methods |
| 9.2.1 |
Derivation of in vitro BMC and BMD values |
| 9.2.2 |
In vitro–in vivo correlation |
| 9.3 |
Discussion and Commentary |
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Chapter 10
Three-Dimensional Cell Culture of Canine Uterine Glands
| 10.1 |
 |
Introduction |
| 10.2 |
Materials |
| 10.2.1 |
Cell culture |
| 10.2.2 |
Histological preparation for light microscopy |
| 10.2.3 |
Histological preparation for electron microscopy |
| 10.3 |
Methods |
| 10.3.1 |
Cell culture |
| 10.3.2 |
Histological preparation for light microscopy |
| 10.3.3 |
Histological preparation for electron microscopy |
| 10.3.4 |
Imaging |
| 10.4 |
Anticipated Results |
| 10.5 |
Discussion and Commentary |
| 10.6 |
Application Notes |
| 10.7 |
Summary Points, References |
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